Selected Publications
Huang HI, Xue Y, Jewell ML, Tan CY, Theriot B, Aggarwal N, Dockterman J, Lin YD, Schroeder EA, Wang D, Xiong N, Coers J, Shinohara ML, Surana NK, Hammer GE.
“A binary module for microbiota-mediated regulation of gd17 cells, hallmarked by microbiota-driven expression of programmed cell death protein 1 (2023). Cell Reports Aug;42(8):112951. doi: 10.1016/j.celrep.2023.112951. PMCID: PMC10588736.”
— Surprisingly, signals from the microbiome are simultaneously hot and cold.
Huang H, Jewell ML, Youssef N, Huang M, Hauser ER, Fee, BE, Rudemiller NP, Privratsky JR, Zhang JJ, Reyes E, Wang D, Taylor GA, Gunn MD, Ko DC, Cook DN, Chandramohan V, Crowley SD and Hammer GE.
“Th17 immunity in the colon is controlled by two novel subsets of colon-specific mononuclear phagocytes (2021). Frontiers in Immunology 12:661290. PMCID: PMC8113646.
— These phagocytes were always there, but totally hidden from view. Glad we found them out because they are really important for colon immunity and colorectal cancer.
Taylor GA, Huang HI, Fee BE, Youssef N, Jewell ML, Cantillana V, Schoenborn AA, Rogala AR, Buckley AF, Feng CG, Vallance BA, Gulati AS, Hammer GE.
“Irgm1-deficiency leads to myeloid dysfunction in colon lamina propria and susceptibility to the intestinal pathogen Citrobacter rodentium (2019). PLoS Pathog 16(5):e1008553. PMCID: PMC7274479”
— An unexpected way to win against pathogenic bacteria in the gut.
Liang J, Zhang JJ, Huang H, Kanayama M, Youssef N, Jin YJ, Reyes EY, Abram CL, Yang S, Lowell CA, Wang D, Shao L, Shinohara ML, Zhang JY, and Hammer GE.
“The ubiquitin-modifying enzyme A20 terminates C-type lectin receptor signals and is a suppressor of host defense against systemic fungal infection (2020). Infection and immunity Jun 15; doi:10.1128/IAI.00048-20”
Yang S, Harding AT, Sweeney C, Miao D, Swan G, Zhou C, Jiang Z, Fitzgerald KA, Hammer G, Bergo MO, Kroh HK, Lacy DB, Sun C, Glogauer M, Que LG, Heaton NS, Wang D.
“Control of antiviral innate immune response by protein geranylgeranylation (2019). Science Advances 5: eaav7999. PMID: 31149635
Wen Y, Rudemiller NP, Zhang J, Lu X, Ren J, Privratsky JR, Griffiths R, Zhang JJ, Hammer GE, Crowley SD.
“C-C motif chemokine receptor 7 exacerbates hypertension through effects on T lymphocyte trafficking (2020). Hypertension 75(3):869-876. PMID: 31983306
Jaslow SL, Gibbs KD, Fricke WF, Wang L, Pittman KJ, Mammel MK, Thaden JT, Flower VG Jr, Hammer GE, Elfenbein JR, Ko DC.
“Salmonella activation of STAT3 signaling by SarA effector promotes intracellular replication and production of IL-10. (2018). Cell reports 23: 3525-36. PMID: 27783947”
Liang J, Huang H, Benzatti F, Karlsson A, Zhang J, Ma A, Hale LP, Hammer GE.
“Inflammatory Th1 and Th17 cells in small intestine are each driven by functionally specialized dendritic cells with distinct requirements for MyD88 (2016). Cell Reports 17: 1330-43. PMID: 27783947”
— Recommended by Faculty of 1000 for special significance in the field.
Kanayama M, Inoue M, Danzaki K, Hammer G, He YW, Shinohara ML.